Abstract
Solar urticaria is a rare form of physical
urticaria mediated by
immunoglobulin E. The lesions appear immediately after the
sun exposure, interfering with the
patient's normal daily
life.
Omalizumab, a monoclonal anti-
IgE antibody, has been recently approved for the
treatment of
chronic spontaneous urticaria, and the latest
reports support its
role also in the
treatment of
solar urticaria. Hereby, we
report a case of
solar urticaria refractory to conventional
treatment strategies, with an excellent response to
treatment with
omalizumab and phototesting normalization.