Las células dendríticas plasmacitoides evocan la respuesta efectora de los linfocitos T citotóxicos específicos para Salmonella / The plasmacytoid dendritic cells evoke Salmonella-specific CTL effector response
To analyze the Salmonella-specific CTL response evoked by pDCs. Materials and
methods:
We used plasmacytoid dendritic cells stained with carboxyfluorescein succinimidyl ester (CFSE) and pulsed with OmpC73, Salmonella Kb- restricted epitopes or S. Typhimurium as targets for cytotoxicity assays.
Results:
Specific lysis was shown to be statistically significant in pDC + OmpC73 for all effectortarget ratios (p≤0.05). For pDC + S. Typhimurium, statistical significance was only observed at a 1100 ratio (p≤0.05) using OmpC73.