Quantitative evaluation of brain volume among elderly individuals in São Paulo, Brazil: a population-based study / Avaliação quantitativa do volume cerebral em um grupo de idosos de São Paulo, Brasil: um estudo de base populacional
Rodrigues, Mariana Athaniel Silva; Rodrigues, Thiago Pereira; Zatz, Mayana; Lebrão, Maria Lúcia; Duarte, Yeda Aparecida; Naslavsky, Michel Satya; Nascimento, Felipe Barjud Pereira do; Amaro Junior, Edson.
Radiol. bras
; 52(5): 293-298, Sept.-Oct. 2019. graf
Artículo
en Inglés
| LILACS | ID: biblio-1040949
Abstract
Objective:
To perform a quantitative analysis of the brain volume of elderly individuals in a population-based sample. Materials andMethods:
This was a radiological assessment and voxel-based quantitative analysis, with surface alignment, of 525 magnetic resonance imaging scans of individuals between 60 and 103 years of age who participated in the Saúde, Bem-estar e Envelhecimento (Health, Well-being, and Aging) study in the city of São Paulo, Brazil.Results:
We noted a median rate of reduction in total brain volume of 2.4% per decade after 60 years of age. Gray and white matter both showed volume reductions with age. The total brain volume/intracranial brain volume ratio differed between males and females.Conclusion:
We have corroborated the findings of studies conducted in the United States and Europe. The total brain volume/intracranial brain volume ratio is higher in men, representing a potential bias for the conventional radiological assessment of atrophy, which is typically based on the evaluation of the cerebrospinal fluid spaces.
Biblioteca responsable:
BR1.1
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