In Argentina, hydrofluoric acidaccidents are a rare reason for consultation, despite being a commonly used substance in laboral activities. It is one of the few caustics with a specific treatment that must be taken into account. We report the case of a 35 year old patient affected by said substance, in which we observe an impairment of the upper limb, presenting on the right palmar region, an erythematous plaque with a blister lesion with posterior scaling and bleeding of the nailbed. The importance of the early clinical suspicion and the proper administration of calcium gluconate would avoid bigger and more extensive lesions