The control of
dyslipidemia using
plants is an important subject of studies since it has numerous benefits in cardiovascular
protection. The objective of this study was to evaluate the effect of three
Camellia sinensis L. teas (green, red, and
white) on
left ventricular hypertrophy and
insulin resistance in
low-density lipoprotein receptor knockout (LDLr-/-)
mice fed a
high-fat diet. The LDLr-/-
mice were divided into four experimental groups Group C standard feed; Group CT standard feed and three teas, Group HL high-fat feed; HLT Group high-fat feed and three teas. The three types of
tea (green, red, and
white) originated from different processing of the
Camellia sinensis L.
plant, and were administered associated once a day at a
dose of 25 mg/kg by gavage for 60 days. The teas partially prevented
hyperlipidemia, the decrease of the
serum levels of
high-density lipoproteins (HDL),
insulin resistance, and increased
C-reactive protein (CRP) levels, and completely prevented
left ventricular hypertrophy in LDLr -/-
mice of the HLT group. In conclusion, the three
Camellia sinensis L. teas used to control genetic
dyslipidemia associated with a
high-fat diet can be used as an auxiliary
treatment associated with the control of
lipid intake, thus promoting cardiac
protection against
hyperlipidemia.