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Rotational thromboelastometry in the perioperative period of cardiac surgeries: cost-effectiveness analysis and budget impact / Tromboelastometria rotacional no período perioperatório de cirurgias cardíacas: custo-efetividade e impacto orçamentário

Santos, André Soares; Oliveira, Ananda Jessyla Felix; Fernandes, Magda Lourenço; Nogueira, José Luiz dos Santos; Noronha, Kenya Valéria Micaela de Souza; Andrade, Mônica Viegas.
J. bras. econ. saúde (Impr.) ; 12(3): 173-188, Dezembro/2020.
Artículo en Inglés | ECOS, LILACS | ID: biblio-1141294

Objective:

The transfusion of blood components and blood products in cardiac surgery patients can be guided by protocols based on standard laboratory tests and/or clinical decisions (Standardof-Care, SOC) or viscoelastic haemostatic assays (VHA). The aim of this study is to evaluate the cost-effectiveness and budget impact of VHAs compared to SOC.

Methods:

A decision tree model was built in TreeAge Pro® 2009. Costs and benefits were taken from the medical literature. The costeffectiveness was evaluated in a base-case scenario and a worst-case scenario, considering low costs of adverse events. The budget impact was evaluated from data taken from Datasus. Cost data were measured in 2019 USD and outcomes were measured in QALYs.

Results:

VHAs were considered dominant in the base-case scenario and very cost-effective in the worst-case scenario (ICER = $ 1,083.21 USD/QALY). The budget impact analysis varied from a cost-saving result in the base-case scenario to a reasonable increase in cost in the worst-case scenario. Since the total market share of the technology is unlikely, a reasonable estimative for the base-case scenario and the worst-case scenario are about -$275 million USD and $132 million USD, respectively.

Conclusion:

We conclude that the VHAs are cost-effective and should be recommended for the use in the perioperative period of cardiac surgeries, especially for patients with a high risk of hemorrhage or coagulation problems.
Biblioteca responsable: BR600