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PIMAPotassium Iodide Point-of-Care Testing for CD4 Counts in Predicting Antiretroviral Initiation in HIV-Infected Individuals in KwaZulu-Natal; Durban; South Africa

Coutsoudis, Anna; Ngomane, Noluthando; Ntoyanto, Siphelele; Ramjee, Gita; Reddy, Shabashini; Reddy, Tarylee; Skhosana, Mandisa; Spooner, Elizabeth.
Artículo en Inglés | AIM | ID: biblio-1272210

Introduction:

Limited information is available on the usefulness of the PIMATM analyser in predicting antiretroviral treatment eligibility and outcome in a primary healthcare clinic setting in disadvantaged communities in KwaZulu-Natal; South Africa.Materials and

methods:

The study was conducted under the eThekwini Health Unit; Durban; KwaZulu-Natal. Comparison of the enumeration of CD4+ T-cells in 268 patients using the PIMATM analyser and the predicate National Health Laboratory Services (NHLS) was undertaken during January to July 2013. Bland-Altman analysis to calculate bias and limits of agreement; precision and levels of clinical misclassification at various CD4+ T-cell count thresholds was performed.

Results:

There was high precision of the PIMATM control bead cartridges with low and normal CD4+ T-cell counts using three different PIMATM analysers (%CV 5). Under World Health Organization (WHO) guidelines (
Biblioteca responsable: CG1.1