SUMMARY
OBJECTIVE:
To assess the
prevalence of altered
ankle-brachial index (<0.9 or >1.3) in
patients with
type 1 diabetes and to compare it with the presence of subclinical
atherosclerosis by
carotid ultrasound.
METHODS:
Prospective,
cross-sectional study in which 45
adults with
type 1 diabetes were evaluated (age 34±10 years, 46.7%
men). The data collected included anamnesis, clinical evaluation, calculation of the
ankle-brachial index (relationship between systolic
blood pressure in the
ankle and
brachial artery), and performance of
carotid ultrasound.
RESULTS:
Thirty-two
patients had
ankle-brachial index >1.3 (66.7%) and no
patient had
ankle-brachial index <0.9. Carotid
echocardiography was performed on 21
patients, 4 (19%) of whom had
atherosclerosis. Age >35 years and
ankle-brachial index >1.4 showed a good correlation with
atherosclerosis (r=0.49, p=0.021; r=0.56, p=0.008, respectively). A model associating age >35 years and
ankle-brachial index >1.4 showed an excellent relationship with
atherosclerosis (r=0.59, p=0.004).
CONCLUSIONS:
Our study showed that
vascular calcification (
ankle-brachial index >1.4) was frequent in this
population with
type 1 diabetes and associated with subclinical
atherosclerosis. A model combining
ankle-brachial index >1.4 and age >35 years showed an excellent correlation with
atherosclerosis and can assist in clinical suspicion and optimize the request for additional tests.