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Beneficial effects of three natural products for the treatment of denture stomatitis: a randomized clinical trial / Efeitos benéficos de três produtos naturais para o tratamento da estomatite protética: um ensaio clínico randomizado

Silva, Paulo Maurício Batista da; Chocano, Ana Paula Chappuis; Venante, Helena Sandrini; Costa, Rodrigo Moreira Bringel da; Silva, Rafaela Alves da; Neppelenbroek, Karin Hermana; Lara, Vanessa Soares; Porto, Vinícius Carvalho.
Arq. odontol ; 57: 141-148, jan.-dez. 2021. ilus, tab
Artículo en Inglés | LILACS, BBO - odontología (Brasil) | ID: biblio-1343550

Aim:

To evaluate the effect of three natural antifungal agents combined with routine denture care on the treatment of DS, using a quantitative mycological culture analysis.

Methods:

Thirty denture wearers with denture stomatitis DS were treated using five substances sterile distilled water (G1), nystatin oral suspension (G2), 20% alcoholic extract propolis (G3), Punica granatumLinné gel (G4), and Uncaria tomentosa gel (G5). The substances were used 3 times a day for 14 days. Quantitative mycological culture analysis of samples collected from the palatal mucosa was performed at three stages before treatment (T0), after 14 days of treatment (T1), and 30 days after treatment completion (T2). Data were evaluated using Kruskal-Wallis and Friedman tests (p < 0.05).

Results:

Palatal mucosa intragroup analysis showed a significant reduction of Candida CFU/mL values for all groups at T1 compared to T0 (p < 0.05). However, they did not present statistical differences when comparing T1 and T2 (p > 0.05). The intergroup analysis demonstrated that there are no statistical differences, regardless of the evaluation time (p > 0.05).

Conclusion:

The natural products tested showed a satisfactory result on DS treatment, which proved to be equivalent to conventional topical therapy with nystatin and to treatment using only regular oral hygiene procedures.
Biblioteca responsable: BR365.1
Ubicación: BR365.1