Enfermedad vascular en pacientes varones con enfermedad de Fabry en hemodiálisis: estudio de cohorte retrospectivo en Argentina / Vascular disease in male patients with Fabry disease on hemodialysis: a retrospective cohort study in Argentina
Estudio de cohorte retrospectivo realizado en tres centros de Argentina entre enero de 2010 y enero de 2017. Se incluyeron pacientes con EF y ERT en hemodiálisis. Se recopiló información sobre aspectos demográficos, clínicos y EV.
a retrospective, cohort study was carried out at three centers in Argentina between January 2010 and January 2017. Hemodialysispatients with FD and ESRD were included. Information was collected regarding demographic, clinical and VE aspects.
Results:
Eight adult (40 ± 4.2 year-old) malepatients with ESRD on hemodialysis (mean time on dialysis 39.1 ± 20.6 months) were included; the mean follow-up time was 55 ± 12 months. Five patients received enzyme replacement therapy during follow-up. Four patients (50%) had VE during follow-up. In three of them the cardiovascular event was fatal. The mean time from admission to dialysis until the onset of VE was 38 ± 8 months.
Conclusion:
50% of the patients with FD and ESRD presented a VE in a mean time of approximately 38 months since their admission to dialysis