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Benzodiazepines utilization in Brazilian older adults: a population-based study / Utilização de benzodiazepínicos em idosos brasileiros: um estudo de base populacional

Freire, Marina de Borba Oliveira; Da Silva, Bruna Gonçalves Cordeiro; Bertoldi, Andréa Dâmaso; Fontanella, Andréia Turmina; Mengue, Sotero Serrate; Ramos, Luiz Roberto; Tavares, Noemia Urruth Leão; Pizzol, Tatiane da Silva Dal; Arrais, Paulo Sérgio Dourado; Farias, Mareni Rocha; Luiza, Vera Lucia; Oliveira, Maria Auxiliadora; Menezes, Ana Maria Baptista.
Rev. saúde pública (Online) ; 56: 1-13, 2022. tab, graf
Artículo en Inglés, Portugués | LILACS, BBO - odontología (Brasil) | ID: biblio-1365954
ABSTRACT OBJECTIVE To evaluate the utilization of benzodiazepines (BZD) in Brazilian older adults, based on the Pesquisa Nacional de Acesso, Utilização e Promoção do Uso Racional de Medicamentos (PNAUM - National Survey of Access, Use and Promotion of Rational Use of Medicines). METHODS The PNAUM is a cross-sectional study conducted between 2013 and 2014, representing the Brazilian urban population. In the present study, we included 60 years or older (n = 9,019) individuals. We calculated the prevalence of BZD utilization in the 15 days prior to survey data collection according to independent variables, using a hierarchical Poisson regression model. A semistructured interview performed empirical data collection (household interview). RESULTS The prevalence of BZD utilization in the older adults was 9.3% (95%CI 8.3-10.4). After adjustments, BZD utilization was associated with female sex (PR = 1.88; 95%CI 1.52-2.32), depression (PR = 5.31; 95%CI 4.41-6, 38), multimorbidity (PR = 1.44; 95%CI 1.20-1.73), emergency room visit or hospitalization in the last 12 months (PR = 1.42; 95%CI 1.18-1.70 ), polypharmacy (PR = 1.26; 95%CI 1.01-1.57) and poor or very poor self-rated health (PR = 4.16; 95%CI 2.10-8.22). Utilization was lower in the North region (PR = 0.18; 95%CI 0.13-0.27) and in individuals who reported abusive alcohol consumption in the last month (PR = 0.42; 95%CI 0.19-0.94). CONCLUSION Despite contraindications, results showed a high prevalence of BZD utilization in older adults, particularly in those with depression, and wide regional and sex differences.
Biblioteca responsable: BR1.1