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Kounis syndrome - Report of 4 cases / Síndrome de Kounis - Relato de 4 casos

Coutinho, Catarina; Neto, Marta; Branco-Ferreira, Manuel; Viegas, Leonor; Pereira-Barbosa, Manuel.
Arq. Asma, Alerg. Imunol ; 4(4): 480-486, out.dez.2020. ilus
Artículo en Inglés | LILACS | ID: biblio-1382072
Kounis syndrome is described as the occurrence of myocardial injury following a hypersensitivity reaction triggered by allergen exposure. The actual incidence is unknown, as most of the information comes from case reports and there are no international recommendations. Kounis syndrome does not seem to be rare but rather underdiagnosed. We report and discuss the clinical presentation and management of 4 cases of Kounis syndrome. All patients presented with anaphylaxis and chest pain. Patient age ranged from 44 to 83 years. Anaphylaxis triggers were nonsteroidal anti-inflammatory drugs and antibiotics. It is important to recognize Kounis syndrome in order to conduct an adequate investigation and prevent further events. A major difficulty is that the treatment of the 2 entities (hypersensitivity reaction and acute coronary syndrome) may worsen each other. Large prospective studies are needed to establish definitive treatment guidelines for these patients.
Biblioteca responsable: BR2717.9