Association between obesity and hospitalization in mild COVID-19 adult outpatients in Brazil: a prospective cohort study
Sartor, Ivaine Tais Sauthier; David, Caroline Nespolo de; Telo, Gabriela Heiden; Zavaglia, Gabriela Oliveira; Fernandes, Ingrid Rodrigues; Kern, Luciane Beatriz; Polese-Bonatto, Márcia; Azevedo, Thaís Raupp; Santos, Amanda Paz; Almeida, Walquiria Aparecida Ferreira de; Porto, Victor Bertollo Gomes; Varela, Fernanda Hammes; Scotta, Marcelo Comerlato; Rosa, Regis Goulart; Stein, Renato T..
Arch. endocrinol. metab. (Online)
; 66(4): 512-521, July-Aug. 2022. tab, graf
Artículo
en Inglés
|
LILACS-Express
| ID: biblio-1403225
ABSTRACT
Objective:
To evaluate the association between obesity and hospitalization in mild COVID-19 adult outpatients in Brazil. Subjects andmethods:
Adults with signs and symptoms suggestive of acute SARS-CoV-2 infection who sought treatment in two hospital (public and private) emergency departments were prospectively enrolled. Patients with confirmed COVID-19 at inclusion were followed by phone calls at days D7, D14 and D28. Multivariable logistic regression models were employed to explore the association between obesity and other potential predictors for hospitalization.Results:
A total of 1,050 participants were screened, and 297 completed the 28-day follow-up and were diagnosed with COVID-19 by RT-PCR. The median age was 37.2 (IQR 29.7-44.6) years, and 179 (60.0%) were female. The duration of symptoms was 3.0 (IQR 2.0-5.0) days, and 10.0 (IQR 8.0-12.0) was the median number of symptoms at inclusion. Ninety-five (32.0%) individuals had obesity, and 233 (78.5%) had no previous medical conditions. Twenty-three participants (7.7%) required hospitalization during the follow-up period. After adjusting, obesity (BMI ≥ 30.0 kg/m2) (OR = 2.69, 95% CI 1.63-4.83, P < 0.001) and older age (OR = 1.05, 95% CI 1.01-1.09, P < 0.001) were significantly associated with higher risks of hospitalization.Conclusion:
Obesity, followed by aging, was the main factor associated with hospital admission for COVID-19 in a young population in a low-middle income country. Our findings highlighted the need to promote additional protection for individuals with obesity, such as vaccination, and to encourage lifestyle changes.
Biblioteca responsable:
BR1.1
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