Antimicrobial resistance of Shiga toxinproducing Escherichia coliisolated from sheep / Escherichia coli produtora de toxina Shiga resistentes a antimicrobianos isoladas de ovinos
Lima, Emanuelle Azambuja; Silveira, Ângela Vitalina Barbosa de Assis; Zaiden, Lucas; Oliveira, Angélica Franco de; Paula, Eric Mateus Nascimento de; Silva, Vera Lúcia Dias da; Souza, Cleusely Matias de; Castelhano, Elaine Cristina; Stella, Ariel Eurides.
Braz. J. Vet. Res. Anim. Sci. (Online)
; 59: e196807, fev. 2022. tab
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| VETINDEX | ID: biblio-1415351
The presence of Shiga toxin-producing Escherichia coli (STEC) and resistance to beta-lactams in healthy sheep represents a potential public health risk. This study aimed to characterize STEC isolates in sheep feces for toxin production and resistance to beta-lactam antibiotics. In the present study, among the 40 isolates, we found a predominance of subtype Stx1 (22/40), followed by subtype Stx1 + Stx2 (11/40), while the less prevalent group was Stx2 (7/40). Also, we found phenotypical resistance to beta-lactam antibiotics in 50% (20/40) of the strains analyzed, forming two groups, one with resistant isolates and the other with non-resistant isolates. The cytotoxicity of the isolates did not vary among the groups. In addition to having this characteristic, some multiresistant isolates produced significant amounts of toxins. This leads to the conclusion that the mechanisms of antimicrobial resistance via beta-lactamases are present in sheep STEC and that the cytotoxicity of those isolates is variable regarding such resistance.(AU)
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BR68.1
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