Changes in the rest-activity rhythm in migraine patients are associated with anxiety symptoms
David, Mírian C.M.M.; Mattos, Marina S.B.; Souto, Jandirlly J.S.; Brito, Sarah A.C.F.; Leite, Etcheverry S.; Valença, Eduardo N.; Galdino, Gilma S.; Sampaio, Patrick G.G.; Moura, Daniel M.C.; Miguel, Mário A.L.; Araújo, John F.; Franco, Carlúcia I.F.; Matos, Rhowena J.B..
Braz. J. Psychiatry (São Paulo, 1999, Impr.)
; 44(6): 611-620, Nov.-Dec. 2022. tab, graf
Artículo
en Inglés
|
LILACS-Express
| ID: biblio-1420518
Objective:
To characterize rest-activity rhythm in chronic migraine (CM) and to investigate the relationship between this rhythm and depressive and anxiety symptoms in patients with CM.Methods:
This was a study of adults aged 20 to 40 years. The rest-activity rhythm of patients with CM (n=23) and non-headache controls (NH, n=23) was assessed by actigraphy for 15 days, and they completed the following assessments Visual Analogue Scale for pain intensity; Headache Diary; Headache Impact Test-6; Morningness-Eveningness Questionnaire; Pittsburgh Sleep Quality Index; Epworth Sleepiness Scale; Beck Depression Inventory; and State-Trait Anxiety Inventory.Results:
Patients with CM showed less activity over 24 hours and more fragmented sleep. Reduced interdaily stability of the rest-activity rhythm was observed, with less robustness of this rhythm in the CM group. Multiple linear regressions revealed a significant association between the rest-activity rhythm and trait anxiety variables in patients with CM, specifically regarding the relative amplitude of the cycle, activity throughout 24 hours and during sleep, and robustness of the rest-activity rhythm.Conclusions:
Our findings provide evidence that the robustness of the rest-activity rhythm, activity throughout 24 hours, and sleep fragmentation are associated with trait anxiety in patients with CM. Clinical trial registration Brazilian Clinical Trials Registry (registration number RBR-4M5J4S).
Biblioteca responsable:
BR1.1
Texto completo
Documentos relacionados