Accuracy of the urine point-of-care circulating cathodic antigen assay for diagnosing Schistosomiasis mansoni infection in Brazil: A multicenter study
Pieri, Otavio Sarmento; Bezerra, Fernando Schemelzer Moraes; Coelho, Paulo Marcos Zech; Enk, Martin Johannes; Favre, Tereza Cristina; Graeff-Teixeira, Carlos; Oliveira, Ricardo Riccio; Reis, Mitermayer Galvão dos; Andrade, Lee Senhorinha de Almeida; Beck, Lilian Christina Nóbrega Holsbach; Favero, Vivian; Fialho, Thainá Rodrigues de Souza; Guimarães, Ricardo José de Paula Souza e; Oliveira, Bruna Souza Santos; Pascoal, Vanessa Fey; Pinheiro, Marta Cristhiany Cunha; Santos, Ronald Alves dos; Silva, Luciano Kalabric; Siqueira, Isadora Cristina de; Souza, Renata Perotto de; Katz, Naftale.
Rev. Soc. Bras. Med. Trop
; 56: e0238, 2023. tab, graf
Artículo
en Inglés
|
LILACS-Express
| ID: biblio-1422897
ABSTRACT
Background:
The World Health Organization recommends a market-ready, urine-based point-of-care diagnostic test for circulating cathodic antigens (CCA) to determine the prevalence of S. mansoni. This study evaluated the performance of the URINE CCA (SCHISTO) ECO TESTE® (POC-ECO), which is currently available in Brazil.Methods:
Residents from eight sites with different prevalence estimates provided one urine sample for POC-ECO and one stool sample for Kato-Katz (KK) and Helmintex® (HTX) testing as an egg-detecting reference for infection status.Results:
None of the study sites had significantly higher POC-ECO accuracy than KK.Conclusions:
POC-ECO is not currently recommended in Brazilian schistosomiasis elimination programs.
Biblioteca responsable:
BR1.1
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