ABSTRACT Although the endovascular repair of descending thoracic aortadiseases is an already consolidated procedure, this approach is not well-established for ascending aorta and arch pathologies. A 71-year-old malepatientwho had undergone an open ascending aorta replacement ten years ago presented with a huge dissected aortic arch aneurysm. Vascular accesses were obtained with ultrasound-guided punctures, followed by aortic arch exclusion using aortic endoprostheses and the chimney-grafttechnique for preserving supra-aortic branches flow. This case demonstrates the feasibility of a totally percutaneous aortic arch repair provided that careful preprocedural planning and a dedicated team are available for such a challenging intervention.