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HLA in Brazilian Ashkenazic Jews with chronic dermatophytosis caused by Trichophyton rubrum

Sadahiro, Aya; Roberto Feresin Moraes, José; Elisa Hue Moraes, Maria; Romero, Matilde; Alves de Lima Gouvea, Nancy; José Gouvea, Celso; Morishi Ogusku, Mauricio; Campbell, Iphis; Zaitz, Clarisse.
Artículo en Inglés | LILACS-Express | ID: biblio-1469522
The frequency of HLA (Human Leucocyte Antigens) was analyzed in 25 non-consanguineous Brazilian Ashkenazic Jews, resident in the city of São Paulo, Brazil, suffering from chronic dermatophytosis caused by T. rubrum, and in 25 non-infected individuals belonging to the same ethnic group. Statistically significant values (p 0.05) were observed for HLA-B14 associated with resistance to chronic dermatophytosis and HLA-DQB1*06 (p=0.05) possibly related to susceptibility. These findings suggest that genes on the chromosome 6, in the region of the major histocompatibility complex, may influence the development of chronic dermatophytosis.
Biblioteca responsable: BR68.1