Forty-five studies with 59 gonorrheaprevalence data points were identified. Fifty data points were for women and represented 21,815 individuals, eight for men encompassing a total of 4,587 individuals, and one for transgender people comprising 345 individuals. The Spectrum-STI estimate for the prevalence of urogenital infection with gonorrhea in women 15-49 in 2020 was 0.63% (95% confidence interval (CI) 0.13-2.23) and was lower than the 1.05% estimated value for 2000 (95% CI 0.36-2.79). The corresponding figures for men were 0.70% (95% CI 0.16-2.44) and 1.14% (95% CI 0.34-3.15). Anal prevalence estimates could not be generated because of insufficient data (three data points).