What is known about the effects of vitamin D in neuropsychiatric lupus?
Karnopp, Thaís Evelyn; Freitas, Vinicius da Silva; Domenico, Andressa Leite Di; Chapacais, Gustavo Flores; Santos, Natália Garcia dos; Freitas, Eduarda Correa; Gasparin, Andrese Aline; Monticielo, Odirlei André.
Adv Rheumatol
; 64: 2, 2024. tab, graf
Artículo
en Inglés
|
LILACS-Express
| ID: biblio-1533543
Abstract Systemic lupus erythematosus (SLE) is an autoimmune disease that can affect several organs and systems. The central and/or peripheral nervous system can suffer from complications known as neuropsychiatric lupus (NPSLE). Studies have associated the manifestations of SLE or NPSLE with vitamin D deficiency. It has been shown that hypovitaminosis D can lead to cognition deficits and cerebral hypoperfusion in patients with NPSLE. In this review article, we will address the main features related to vitamin D supplementation or serum vitamin D levels with neuropsychiatric manifestations, either in patients or in animal models of NPSLE.
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