Differential Diagnosis between Neoplastic and Non-Neoplastic Brain Lesions in Radiology / Diagnóstico diferencial entre lesões cerebrais neoplásicas e não neoplásicas em radiologia
Rabelo, Nícollas Nunes; Silveira Filho, Luciano José; Silva, Bruno Nascimento Bithencurt da; Cunha, Christien Dannemberg; Furtado, Igor de Souza; Valli, Daniel Alves Branco; Pereira, Vitor Hugo Honorato; Passos, George Santos dos; Sant'Anna, Marco Aurélio Ferrari; Rabelo, Neiffer Nunes; Dias, Luiz Antônio Araujo; Dias Junior, Luiz Antônio Araujo; Tanaka, Koji; Plastina, Fernando Eduardo.
Arq. bras. neurocir
; 35(1): 45-61, Mar. 2016. ilus
Artículo
en Inglés
| LILACS | ID: biblio-827326
Introduction The observation of multiple lesions in a skull computed tomography (CT) scan is always cause for concern because of the frequent possibility of neoplastic etiology, although granulomatous, infectious, vascular, iatrogenic, demielinating, trauma, parasitic diseases, and strokes can produce a similar aspect on radiology. A wide range of non-neoplastic conditions can mimic a brain tumor, both clinically and radiologically, representing a potential pitfall for physicians involved in patient care. The study's goal is to alert specialists to the possibility of other neoplastic and nonneoplastic etiologies in the differential diagnosis of hypodense lesions in non-contrast. Methods We performed a literature review using PubMed, Medline, Science Direct, Embase, Clinical Trials, Ebsco, and Scielo. Articles were selected in the period of 1986 to 2015. Discussion Knowledge of various etiologies when with multiple lesions appear on computed tomography allows specialists to guide the diagnosis to appropriate treatment, avoiding the irradiation of non-neoplastic lesions and unnecessary surgeries. The most common lesions were the neoplasm (74% to 86%), especially gliomas, followed by infections (8% to 15%), and infarcts (0.6% to 6%), which represent nonneoplastic lesions. Conclusion Given the relatively high percentage of wrong neuroradiology diagnoses, most cases may require histological diagnosis, because even magnetic resonance imaging (MRI) renders difculties in distinguishing such lesions.
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