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Stroke recurrence in the different subtypes of ischemic stroke. The importance of the intracranial disease / Recorrência nos diferentes subtipos de acidente vascular cerebral isquêmico. A importância da doença intracraniana

Lange, Marcos C; Ribas, Gustavo; Scavasine, Valeria; Ducci, Renata Dal-Prá; Mendes, Danielle C; Zétola, Viviane de Hiroki Flumignan; Cabral, Norberto; Rundek, Tatjana.
Arq. neuropsiquiatr ; 76(10): 649-653, Oct. 2018. tab
Artículo en Inglés | LILACS | ID: biblio-973922
ABSTRACT The aim of the study was to analyze the long-term recurrence rate in patients with a first-ever ischemic stroke secondary to intracranial large artery atherosclerosis (LAA) in a Brazilian population.

Methods:

All stroke patients admitted to the hospital between October 2012 and September 2015 were evaluated. The stroke mechanism subtypes were classified as cardioembolism, LAA, small-vessel occlusion, other determined etiologies, and stroke of undetermined etiology.

Results:

The 359 first-ever ischemic stroke patients were followed up for a mean time of 21.6 ± 15.1 months. The LAA intracranial (38.9%) and extracranial (24.6%) stroke patients presented with a higher stroke recurrence. Intracranial LAA [HR, 10.2 (3.6-29.1); p < 0.001] and extracranial LAA [HR, 5.05 (1.79-14.2); p = 0.002] were the only conditions to show positive correlation with the recurrence rate, after adjusting for risk factors, thrombolysis, and National Institutes of Health Stroke Scale score at admission.

Conclusion:

Intracranial LAA presents a higher incidence of recurrence of ischemic stroke when compared with other etiologies in a Southern Brazilian population.
Biblioteca responsable: BR1.1