Autotrasplante de células progenitoras hematopoyéticas en esclerosis múltiple. / [Autotransplantation of hematopoietic progenitor cells in multiple sclerosis]
Fernández, J; Correale, J; Campestri, R; Koziner, B.
Medicina [B Aires]
; 59(3): 287-92, 1999.
Artículo
en Español
| BINACIS | ID: bin-39958
Multiple sclerosis (MS) is an autoimmune demyelinating disease exhibiting great clinical variability. For control of its primary and secondary progressive variants, treatment has met with limited success. In recent years, increasing experience has been gained with the administration of high dose chemotherapy supported by the autologous infusion of hematopoietic progenitor cells (HPC), in some instances depleted of T cells. The European and International Registry of Hematopoietic Cell Transplantation for Autoimmune Diseases include 43 MS patients. BEAM was the most frequently used conditioning therapy. Treatment related mortality was 7
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