Large-scale evaluation of a rapid diagnostic test for diarrhea caused by enterotoxigenic Escherichia coli targeting the heat-labile toxin
Henrique, Camila; Caetano, Bruna Alves; Mitsunari, Thaís; dos Santos, Luis Fernando; Piazza, Roxane Maria Fontes; Rocha, Letícia Barboza.
J. Microbiol. Methods
; 144: p. 125-127, 2018.
Artículo
en Inglés
| SES-SP, SESSP-IBPROD, SES-SP | ID: but-ib14983
We standardized an immunochromatographic test (IC) for heat-labile toxin I (LT-I) detection using LT-I antibodies and a specific platform containing the apparatus for application, assembly and cutting. IC detected as little as 62.5 ng/mL of purified LT-I toxin and presented 91% sensitivity, 99.5% specificity and 96.0% accuracy, thereby proving to be an excellent point-of-care test for the diagnosis of enterotoxigenic E. coli infection in low-income countries.
Biblioteca responsable:
BR78.1
Ubicación: BR78.1
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