Despite several conventional potent antibacterial
therapies,
bacterial infections pose a significant threat to
human health because they are emerging as the leading
cause of death worldwide. Due to the development of
antibiotic resistance in
bacteria, there is a pressing demand to discover novel approaches for developing more effective
therapies to treat multidrug-resistant bacterial
strains and
biofilm-associated
infections. Therefore,
attention has been especially devoted to a new and emerging branch of
science "
nanotechnology" to design non-conventional antimicrobial
chemotherapies. A range of
nanomaterials and nano-sized carriers for conventional
antimicrobial agents have fully justified their potential to combat
bacterial diseases by reducing
cell viability, by attenuating
quorum sensing, and by inhibiting/or eradicating
biofilms. This
communication summarizes emerging nano-antimicrobial
therapies in treating
bacterial infections, particularly using antibacterial,
quorum quenching, and anti-
biofilm nanomaterials as new approaches to tackle the current challenges in combating
infectious diseases.