A clinical characterization, validated by laboratory results of 41 patients with metabolic syndrome (69,5 percet), selected of a sample of 59 overweighed and obese adults was carried out by means of a sampling through conglomerates and stratified by gender, detected according to the criteria of the National Program of Education on Cholesterol and assisted in Mario Gutiérrez Polyclinic in Holguín from November, 2008 to June, 2009. Statistical values were obtained through the Student t and X2 tests. Men with metabolic syndrome had higher levels of systolic arterial tension, total cholesterol and triglycerides than men without the disease; the women with that condition also had higher weight, body mass index and wider abdominal circumference. An association between reactive C protein, microalbuminuria and the alteration of glycemia with the mentioned syndrome was proven, from where it was concluded that it was very important to confirm its presence taking into account the high risk that implied for the cardiopathies and diabetes mellitus occurrence(AU)