Isolation of dengue 2 virus from a patient with central nervous system involvment (transverse myelitis)
Leão, Raimundo N. Q; Oikawa, Teichi; Rosa, Elisabeth S. T; Yamaki, José T; Rodrigues, Sueli G; Vasconcelos, Helena B; Sousa, Maria R. S; Tsukimata, Jaime K; Azevedo, Raimunda S. S; Vasconcelos, Pedro F. C.
Rev. Soc. Bras. Med. Trop
; 35(4): 401-404, 2002. tab
Artículo
en Inglés
| BVSDIP, FIOCRUZ | ID: dip-1858
A dengue fever case is described in a 58-year-old male patient with febrile illness and thrombocytopeniacomplicated by neurological involvement characterized by transverse myelitis followed by weakness of bothlegs and flaccid paralysis. Muscle strength was much diminished and bilateral areflexia was observed. Dengue2 (DEN-2) virus was isolated and the patient sero-converted by hemagglutination-inhibition and IgM-ELISAtests. The RT-PCR test was positive to DEN-2 in acute phase serum and culture supernatant, but negative inthe cerebrospinal fluid. After three weeks of hospitalization the patient was discharged. No other infectiousagent was detected in the blood and cerebrospinal fluid samples. The patient had full recovery from paralysissix months after the onset of DEN-2 infection...(AU)
Biblioteca responsable:
BR275.1
Ubicación: BR275.1; PCIEC2002
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