Risk factors for Dengue virus infection in rural Amazonia: population-basedcross-sectional surveys
Silva-Nunes, Monica da; Souza, Vanda A F de; Pannuti, Cláudio S; Sperança, Márcia A; Terzian, Ana Carolina B; Nogueira, Maurício L; Yamamura, Anna M Y; Freire, Marcos S; Natal S. da Silva; Malafronte, Rosely S; Muniz, Pascoal T; Vasconcelos, Helena B; Silva, Eliana V. P; Vasconcelos, Pedro F C; Ferreira, Marcelo U.
Am J Trop Med Hyg
; 74(4): 485-494, 2008. ilus, tab
Artículo
en Inglés
| BVSDIP, FIOCRUZ | ID: dip-2848
A comparison of dengue virus (DENV) antibody levels in paired serum samples collected from predominantly DENV-naive residents in an agricultural settlement in Brazilian Amazonia (baseline seroprevalence, 18.3 percent) showed a seroconversion rate of 3.67 episodes/100 person-years at risk during 12 months of follow-up. Multivariate analysis identified male sex, poverty, and migration from extra-Amazonian states as significant predictors of baseline DENV seropositivity, whereas male sex, a history of clinical diagnosis of dengue fever, and travel to an urban area predicted subsequent seroconversion. The laboratory surveillance of acute febrile illnesses implemented at the study site and in a nearby town between 2004 and 2006 confirmed 11 DENV infections among 102 episodes studied with DENV IgM detection, reverse transcriptase-polymerase chain reaction, and virus isolation; DENV-3 was isolated. Because DENV exposure is associated with migration or travel, personal protection measures when visiting high-risk urban areas may reduce the incidence of DENV infection in this rural population.(AU)
Biblioteca responsable:
BR275.1
Ubicación: BR275.1; PCIEC2008
Texto completo
Documentos relacionados