Understanding the clinical spectrum of complicated Plasmodium vivax malaria: a systematic review on the contributions of the Brazilian literature
Lacerda, Marcus V; Mourão, Maria PG; Siqueira, André M; Magalhães, Belisa M; Martinez-Espinosa Flor E; Santana Filho, Franklin S; Brasil, Patricia; Ventura, A. M. R. S; Tada, Mauro S; Couto, Vanja SCD; Silva, Antonio R; Alecrim, Maria GC.
Malar j
; 11(1): 1-18, 2012. tab
Artículo
en Inglés
| BVSDIP, FIOCRUZ | ID: dip-3363
ABSTRACT The resurgence of the malaria eradication agenda and the increasing number of severe manifestation reports has contributed to a renewed interested in the Plasmodium vivax infection. It is the most geographically widespread parasite causing human malaria, with around 2.85 billion people living under risk of infection. The Brazilian Amazon region reports more than 50 per cent of the malaria cases in Latin America and since 1990 there is a marked predominance of this species, responsible for 85 per cent of cases in 2009. However, only a few complicated cases of P. vivax have been reported from this region. A systematic review of the Brazilian indexed and non-indexed literature on complicated cases of vivax malaria was performed including published articles, masters' dissertations, doctoral theses and national congresses' abstracts. The following information was retrieved patient characteristics (demographic, presence of co-morbidities and, whenever possible, associated genetic disorders); description of each major clinical manifestation. As a result, 27 articles, 28 abstracts from scientific events' annals and 13 theses/dissertations were found, only after 1987. Most of the reported information was described in small case series and case reports of patients from all the Amazonian states, and also in travellers from Brazilian non-endemic areas. The more relevant clinical complications were anaemia, thrombocytopaenia, jaundice and acute respiratory distress syndrome, present in all age groups, in addition to other more rare clinical pictures...(AU)
Biblioteca responsable:
BR275.1
Ubicación: BR275.1; PCIEC2012
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