Relationship between iron deficiency anemia and febrile seizures
Amirsalari, Susan; Keihani Doust Zarrin, Taj; Ahmadi, Mostafa; Sabouri, Amin; Kavemanesh, Zohreh; Afsharpeyman, Shahla; Torkaman, Mohammad; Ghazavi, Yasaman.
IJCN-Iranian Journal of Child Neurology. 2010; 4 (1): 27-30
en Inglés
| IMEMR | ID: emr-123714
Febrile seizure is the most common convulsive disorder in childhood. The role of iron in metabolism of neurotransmitters and carrying oxygen to the brain suggests the possibility of a relationship between iron deficiency anemia and febrile seizures. The aim of this study was to investigate the relationship between iron deficiency anemia and febrile seizures. This case - control study was performed on 132 cases and 88 controls, aged 9 months to 5 years, from July 2007 to June 2009 in Baqyiatallah Hospital. Patients were selected using simple random sampling. The case group included children with first febrile seizure [core temperature over 38.5[degree sign] C during seizure] without a central nervous system infection or an acute brain insult. The control group included children suffering from a febrile illness without seizure. Iron deficiency anemia was defined with one of these laboratory indexes 1]Hemoglobine [Hb] <10.5mg/dl2] Plasma ferritin <12ng/dl 3] Mean corpuscular volume [MCV] <70 fl. The data collected from patients were analyzed with SPSS.13 software. Low plasma ferritin was found in 35 cases [26.5%] compared to 26 controls [29.5%], low Hb level was found in 4 cases [3%] compared to 6 controls [6.8%] and low MCV was found in 5 cases [3.8%] compared to 6 controls [6.8%]. There was no significant difference in plasma ferritin, Hb level and MCV indices between the two group. Considering the above-mentioned results, there is no relationship between iron deficiency anemia and febrile seizures
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