Nasopharyngeal carcinoma [NPC] is a polygenic
disease related to a variety of factors. With the development of the
microRNAs [
miRNAs]
technique,
researchers found a close link between
miRNAs and NPC. Differentially expressed
miRNAs exist in NPC and normal nasopharyngeal
tissues;
radiotherapy and
chemotherapy also
affect the expression of
miRNAs in NPC
tissues. Further studies showed that dysregulation and
ectopic expression of
miRNAs were involved in the occurrence and development of NPC by affecting the expression of
oncogenes or
tumor suppressor genes, or acting on relevant
signal transduction pathways. It is of great significance to investigate the
miRNAs related to the occurrence and development of NPC for the prevention and
treatment of NPC