The management of
urolithiasis in
patients with
haemophilia poses a real challenge to the
urologist. We conducted a systematic
literature review to assess the
safety and
efficacy of extracorporeal
shock wave lithotripsy [ESWL] in the
treatment of
urolithiasis in hemophiliacs. A
systematic review was conducted by using the
National Library of Medicine [
PubMed]
search engine between January 1985 and June 2013. We've used these key words [
haemophilia] and [extracorporeal
shock wave lithotripsy]. All articles dealing with the
treatment of
nephrolithiasis by ESWL in
patients with
hemophilia were included. Two independent reviewers extracted the data from each article. The data was included into a
systematic review and analyzed. A total of 12 medical articles were selected with a total of 25
patients. The stone size varies from 6 to 21 mm. The substitution of the deficient
clotting factor started the day before the ESWL. ESWL was effective in all
patients except one aTter 1-6 sessions /
patient. An ultrasound was performed after the
procedure to look for potential
bleeding complications. The
judgment of the substitution
therapy depends on the
patient's condition, the presence of
hematuria and the absence of signs of
bleeding. Major
bleeding complications were observed in 4
patients. With effective substitution of deficient
clotting factors, ESWL is a safe and low
morbidity method in the
treatment of
urinary calculi in hemophiliacs