In vitro anti-platelet aggregation effects of fourteen fruits and vegetables
Cen, Chen; Qian, Zhang; Feng Qin, Wang; Chun Hong, Li; Yuan Jia, Hu; Zhi Ning, Xia; Feng Qing, Yang.
Pakistan Journal of Pharmaceutical Sciences. 2019; 32 (1): 185-195
en Inglés
| IMEMR | ID: emr-203051
In the present study, the anti-platelet aggregation activity of 14 vegetables and fruits was tested in vitro. The aqueous, 90% ethanol and ethyl acetate extracts, as well as concentrated juices of 14 foods [fruits and vegetables] were prepared, and the anti-platelet aggregation activity of those extracts was analyzed on a platelet aggregation analyzer in vitro with adenosine 5'-diphosphate [ADP], bovine thrombin [THR] and arachidonic acid [AA] as aggregation inducers, respectively. Aspirin [ASP] was used as the positive control. A number of the tested foods had inhibitory effects in concentration-dependent manner on platelet aggregations induced by various agonists. Especially, some foods such as lemon, leek, garlic, scallion, ginger, tomato and grapefruit showed good anti-platelet aggregation effect similar or higher than that of positive control group i.e. aspirin [ASP]. The results of present study provide scientific reference for reasonable selection of daily dietary with supplementary curative effects or prevention of cardiovascular diseases [CVD]
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