Pneumocystis Carinii and
Trichosporon beigelii are
opportunistic infections in
immunocompromised patients. We
report a case of a young lady
who underwent haemopoeitic
stem cell transplantation for relapsed
acute lymphoblastic leukemia. This 25 years old
female developed
fever, dry
cough and rapidly progressive dyspnoea during post
transplant neutropenia and was found to be suffering from
Pneumocystis carinii pneumonia. She was successfully treated with
Co-trimoxazole. The
patient again presented with
similar symptoms on day 55 post
transplant. This
time Trichosporon beigelii was isolated from
bronchoalveolar lavage and she responded to prompt antifungal
therapy. Other
complications encountered during the subsequent
course were extensive
subcutaneous emphysema and
spontaneous pneumothorax that required
chest intubation and brief
hospitalization. The
patient is presently nine months post
transplant and is asymptomatic