Granuloma annulare is a polymorphic granulomatous
disease of the
skin. It has a chronic
course and
affects mainly
children and
young adults. We
report two cases of generalized
granuloma annulare in
children successfully treated with
antimalarials.Two
children, 6 and 12 years of age, without clinical
history, presented with multiple
granuloma annulare lesions which did not respond to potent topical
steroids.
Blood glucose level was normal. These lesions responded to
small doses of
antimalarials. No side effects were noticed.Compared with other
drugs, with potential important side effects for
children.
Small doses of
antimalarials might be beneficial in the
treatment of generalized
granuloma annulare