Diffuse and disseminated cutaneous leishmaniasis: clinical cases experienced in Ecuador and a brief review
Hashiguchi, Yoshihisa; Gómez, Eduardo L; Martini, Luiggi R; Velez, Lenin N; Uezato, Hiroshi.
Trop Med Health
; 44(2): 1-9, March 14, 2016.
Artículo
en Inglés
| ECUADOR | ID: equ-7040
Background:
In Ecuador, cutaneous leishmaniasis (CL) is prevalent countrywide, but only one case of diffuse-CL and two cases of disseminated-CL were experienced during our research activities more than 30 years from 1982 to date. These three patients suffered from multiple lesions distributed at a wide range of the body surface,revealing difficulty to clinically differentiate each other.Methods:
There is a considerable confusion of the use and/or differentiation of the terminologies (terms) between the two disease forms, diffuse-CL and disseminated-CL. One of the aims of the present study is to clarify the difference between the two disease forms, mainly based on the cases experienced in Ecuador.Results:
The disseminated-CL case newly reported here was clinically very similar to the diffuse-CL case, but the former showed the following marked differences from the latter (1) the organisms isolated were identified as the parasites of Leishmania (Viannia) guyanensis/panamensis, which are also known as the causative agents of disseminated-CL in different endemic countries of the New World; (2) the patient was sensitive against antimonials; and (3) mucosal involvement was observed, which is never observed in diffuse-CL.Conclusions:
In the text, three clinical cases, one diffuse-CL and two disseminated-CL, were presented. Furthermore, a bibliographic comparison of the features between the two disease forms was made, and a brief comment was also given.(AU)
Biblioteca responsable:
EC107
Ubicación: Biomed Central
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