The ZARADEMP Project on the incidence, prevalence and risk factors of dementia (and depression) in the elderly community: II. Methods and first results
There is a pressing need to identify environmental risk factorsof dementia and depression in the elderly.
Aims:
To describe the methods and first results of the ZARADEMP Project, the firstpsychiatric study to document risk factors in incident cases of dementia (and depression)in a Southern European elderly population.
Method:
A three-wave (baseline and two follow-up waves) epidemiological study toidentify incident cases of dementia (and depression) was completed in a representativesample population. Valid Spanish versions of case-finding instruments, including theGeriatric Mental State (GMS) were administered by standardized researchers. The incidentcases, diagnosed by a panel of psychiatrists using DSM-IV criteria, will be includedin a case-control study.
Results:
Response rate was acceptable (63.6% in Wave I, 872% in Wave II and 858%in Wave III), and 4,803 individuals completed Wave I. Diagnostic agreement was achievedin 91.4% of probable cases presented to the panel, and a total of 146 incident cases ofdementia were identified.
Conclusions:
We feel confident that modern epidemiological requirements have beenfulfilled and the statistical power in the calculations of risk will be acceptable (AU)