A non-informative cue (C) elicits an inhibition of manual reaction time(MRT) to a visual target (T). We report an experiment to examine if thespatial distribution of this inhibitory effect follows Polar or Cartesiancoordinate systems. C appeared at one out of 8 isoeccentric (7o) positions,the C-T angular distances (in polar coordinates) were 0º or multiples of 45ºand ISI were 100 or 800ms. Our main findings were (a) MRT was maximalwhen C- T distance was 0o and minimal when C-T distance was 180o and (b)besides an angular distance effect, there is a meridian effect. When C and Toccurred in the same quadrant, MRT was longer than when T and C occurredat the same distance (45o) but on different sides of vertical or horizontalmeridians. The latter finding indicates that the spatial distribution of the cueinhibitory effects is based on a Cartesian coordinate system