Actividad de albendazol y los aceites esenciales de menta (Mentha piperita) y manzanilla (Matricaria chamomilla) frente Anisakis tipo I / Activity of albendazole and essential oils of peppermint (Mentha piperita) and chamomile (Matricaria chamomilla) against Anisakis type I
Se ensayó tanto in vitro como in vivo, la actividad larvicida de la mezcla de los aceites esenciales utilizando albendazol como fármaco de referencia y midiéndo su eficacia mediante un modelo estadístico.
The in vitro and in vivo experiments both evidenced that the larvicidal activity of essential oils, was higher than the Albendazole activity. In the in vitro assay, at concentrations of 250 and 187.5 μg/ml, the mortality was 100% with the mixture of essential oils while albendazole was ineffective at the concentrations studied. In the in vivo assay, the mixture of essential oils, was significantly more effective in the reduction of numbers of lesions with rats in comparison to albendazoletreatments and control. Albendazole did not significantly reduce the percentage of lesions caused by larvae vs. control.