Artículo
en Inglés
| IBECS (España) | ID: ibc-141410
Background and
Objectives:
Apathy is a behavioral syndrome that often co-occurs with depression. Nonetheless, the etiology of apathy and depression may be different. We hypothesized that apathy occurs more often in depressed compared to non-depressed older persons; and that independent correlates for apathywill be different in depressed and non-depressed older persons.
Methods:
In this cross-sectional study of Netherlands Study of Depression in Older Persons (NESDO), a total of 350 depressed older persons according to the Composite International Diagnostic Interview (CIDI) and 126 non-depressed older persons, aged at least 60 years were recruited in several Medical Centres and general practices. In both depressed and non-depressed older persons, those with and without apathy as assessed with the Apathy Scale (score greater than or equal to 14) were compared with regard to socio-demographic, clinical, and biological characteristics.
Apathy occurred frequently among both depressed and non-depressed older persons. Among depressed older persons, apathy appeared to be a symptom of more serious depression, whereas among non-depressed personsapathy was associated with increased CRP being a marker for immune activation, suggesting a different a etiology for apathy in its own right (AU)