Consumption of fructose rich industrialized beverages in patients with biopsy-proven non-alcoholic fatty liver disease: a cross-sectional study
Armiliato, Geyza Nogueira de Almeida; Nardelli, Mateus Jorge; Ferolla, Sílvia Marinho; Lima, Érika Cristina; Lisboa, Quelson Coelho; Vidigal, Paula Vieira Teixeira; Ferrari, Teresa Cristina de Abreu; Couto, Claudia Alves.
Nutr. clín. diet. hosp
; 40(2): 17-24, 2020. tab
Artículo
en Inglés
| IBECS (España) | ID: ibc-198965
INTRODUCTION:
Non-alcoholic fatty liver disease (NAFLD) ranges from simple steatosis to nonalcoholic steatohepatitis (NASH) and liver fibrosis. Recently, consumption of high fructose corn syrup (HFCS) has been associated with NAFLD development.OBJECTIVE:
The aim of this study was to investigate the relationship between consumption of HFCS and NAFLD associated metabolic factors and disease progression.METHODS:
This cross-sectional study included 51 patients with biopsy-proven NAFLD who underwent biochemical tests, anthropometrical assessment and full-day dietary evaluation including industrialized beverages quantification.RESULTS:
Individuals were 80% female, with 54 ± 12 years old, 96% with central obesity, 75% with insulin resistance or diabetes mellitus and were separated according to industrialized beverage intake < 7 and ≥ 7 coups/week (i.e., daily). Daily consumption of HFCS was associated with obesity (P = 0.04), hypertriglyceridemia (P = 0.05), higher serum triglycerides (P = 0.03) and VLDL (P = 0.01). There was a significant correlation (R = 0.29; P = 0.04) between consumption of industrialized beverages and increased serum triglycerides. We found no association between daily HFCS intake and NASH diagnosis or presence of fibrosis.CONCLUSION:
Excessive consumption of HFCS in industrialized beverages was associated with obesity, hypertriglyceridemia and high levels of blood triglycerides in patients with NAFLD
No disponible
Asunto(s)
Humanos Masculino Femenino Adulto Persona de Mediana Edad Anciano Fructosa/metabolismo Hígado Graso/metabolismo Enfermedad del Hígado Graso no Alcohólico/metabolismo Jarabe de Maíz Alto en Fructosa/efectos adversos Obesidad/epidemiología Hipertrigliceridemia/epidemiología Biopsia/métodos Jugos de Frutas y Vegetales/efectos adversos Jarabe de Maíz Alto en Fructosa/metabolismo Estudios Transversales
Biblioteca responsable:
ES1.1
Ubicación: BNCS
powered by iAHx-2.18-89
Biblioteca Virtual en Salud