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How should microbiology laboratories interpret cultures of the sonicate of closed needleless connectors? / ¿Cómo deben los laboratorios de microbiología interpretar los cultivos del «sonicado» de los conectores cerrados sin aguja?

Pérez-Granda, María Jesús; Barrio, José María; Cruces, Raquel; Alonso, Beatriz; Martín-Rabadán, Pablo; Collado, Inmaculada; Guembe, María.
Enferm. infecc. microbiol. clín. (Ed. impr.) ; 39(2): 72-77, Febrero, 2021. tab, graf
Artículo en Inglés | IBECS (España) | ID: ibc-208554

Introduction:

Our objective was to determine whether there is a cut-off in the needleless connectors’ (NCs) cultures that when combined with skin cultures it was as efficient as conventional superficial cultures to rule-out catheter colonization (CC) and catheter-related bloodstream infection (CRBSI).

Methods:

During 10 months, we collected samples and then we analyzed the validity values of skin+NCs cultures for CC and CRBSI considering the best cut-off showing at least >90% of specificity to have a high negative predictive value using a ROC curve.

Results:

We collected a total of 167 catheters. The optimal cut-off of NCs culture was 1000cfu/NC. The validity values for CC and CRBSI combining skin cultures and NCs cultures using the selected cut-off were, respectively S, 42.9%/16.7%; SP, 83.6%/75.8%; PPV, 27.3%/2.5%; and NPV, 91.0%/96.0%.

Conclusions:

The combination of skin cultures and quantitative NCs cultures could be used for ruling-out CC and CRBSI.(AU)
Biblioteca responsable: ES1.1
Ubicación: ES15.1 - BNCS