Pharmacological Chemolysis of Uric Acid Lithiasis in A Patient with Crohns Disease
Gras Martínez, Rosa Marta; Diranzo García, Marta; Álvarez Barrera, Ariana; Beltrán Puig, Miguel; Martínez Martínez, Fernando; López Alcina, Emilio.
Arch. esp. urol. (Ed. impr.)
; 76(10): 823-828, diciembre 2023. tab, ilus
Artículo
en Inglés
| IBECS (España) | ID: ibc-229543
Patients with chronic diarrhoea or ileostomies suffer from electrolyte and urinary disorders and are prone to developing uricacid or calcium oxalate stones. Evidence is lacking regarding the management of uric acid stones in patients with inflammatorybowel diseases. We present the case of a male patient with Crohns disease and carrying an ileostomy. He was diagnosed with uricacid urolithiasis (stone size of 11 mm located in the left pyeloureteral junction) after presenting to the emergency room during anepisode of left renal colic. Results of the 24-hour urinalysis showed an acidic pH (pH <5), consistent with hyperuricosuria. Thesuspicion of uric acid lithiasis was confirmed after performing an X-ray diffraction analysis of a lithiasic fragment that passedduring acute renal colic. The patient was prescribed with urinary alkalinisers (medical treatment) and dietary recommendations.After 12 months of treatment and urine pH monitoring, the patient achieved complete chemolysis while maintaining the stabilityof his underlying Crohns disease. The patient had no complications during follow-up, referring adequate gastrointestinal toleranceto treatment and denying side effects. The patient remains asymptomatic and is being followed-up on an outpatient basis.He continues on prophylactic treatment (Lit-Control® pH Up) to maintain the pH in the non-acidic range. (AU)
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Ubicación: ES15.1 - BNCS
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