We
report the case of a 42 years old
male, with a
bipolar disorder and receiving
lithium therapy,
valproic acid and
clonazepam. Due to an exacerbation of his underlying
disease, he was admitted to a psychiatric clinic and received 50 mg of intramuscular
chlorpromazine in 2 ocasions. Afterwards, the
patient had an alteration of conciousness,
fever reaching 39ºC and generalized
muscular rigidity.
Laboratory work-up showed a normal
brain CT scan, a diffuse slowness in the
EEG and a creatinphosphokinase that reached values of 3.040 U/l. He was transferred to an
intensive care unit and treated with
sodium dantrolene and
bromocriptine, obtaining a good clinical response