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Seminoma espermatocítico associado a rabdomiossarcoma de testículo / Spermatocytic seminoma associated with rhabdomyosarcoma of the testis

Di Piero, Antonio Celso; Gugliotta, Antonio; Billis, Athanase.
J. bras. urol ; 25(1): 91-2, jan.-mar. 1999. ilus
Artículo en Portugués | LILACS | ID: lil-246349
The authors present a rare case of spermatocytic seminoma associated to rhabdomyosarcoma of the testicle. The anatomopathological examination after radical left orchiectomy revealed cells that are characteristics of rhabdomyosarcoma. The diagnosis was confirmed by an immunohistochemical study that showed as stron positive for specific muscle actin (HHF35) and sarcomeric actin. In other areas of the tumor, there were cells resembling seminoma, some of them more voluminous and with spermatocyte characteristics, leading to a diagnosis of spermatocytic seminoma. During staging examinations, the patient shown a retroperitoneal lymphadenomegaly in the computed tomography scan and was submitted to 3 cycles of polichemotherapy with cisplatin, etoposide and bleomycin (BEP), followed by radiotherapy on the left iliac and paraortic lymphatic ganglions. The control through computed tomography after chemotherapy and radiotherapy shown regression of the lymphadenomegaly. The patient continues to be rigorously followed, since the sarcomatous component ordinarily has high recurrence rates and poor prognosis
Biblioteca responsable: BR408.1