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Incidencia de labio leporino y paladar hendido en la maternidad del Hospital Clínico de la Universidad de Chile y en las maternidades chilenas participantes en el estudio colaborativo latino americano de malformaciones congénitas, ECLAMC, período 1991-1999 / Incidence of orofacial cleft at Universidad de Chile maternity hospital and other hospitals participating in the Latin American collaborative study of congenital malformations, ECLAMC

Nazer Herrera, Julio; Hubner G., María Eugenia; Catalán M., Jorge; Cifuentes Ovalle, Lucía.
Rev. méd. Chile ; 129(3): 285-93, mar. 2001. tab
Artículo en Español | LILACS | ID: lil-286864

Background:

ECLAMC is a registry, aimed to assess the incidence of congenital malformations, that started in 1967 and Chile incorporated to it in 1969.

Aim:

To report the incidence of cleft lip/palate, updated to 1999 in the University of Chile Maternity Hospital and other Chilean hospitals participating in the ECLAMC. Patients and

methods:

A review of the ECLAMC database that registers all births or stillbirths of more than 500 g.

Results:

The incidence of orofacial cleft, at the University of Chile Maternity Hospital, in the period 1991-1999 was 17.8 per 10000 (12.6 for cleft lip and 5.2 for cleft palate). The incidence in the rest of participating hospitals was 12.04 and 4.6 respectively. Males had a higher incidence of cleft lip and 80 percent of children with cleft palate, had other malformations, most of them as part of a syndrome (13 and 18 trisomy, holoproscencephalia, Pierre Robin, Apert en EE syndromes, anencephaly etc). In three of 12 children with cleft lip but without cleft palate, there was a relative with the same malformation.

Conclusions:

It is proposed that both entities, cleft lip with or without cleft palate and cleft palate without cleft lip, are two etiopathogenically different conditions
Biblioteca responsable: CL1.1