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Evaluación de la respuesta inmune celular inducida en ratones Balb/C por la proteína de envoltura del virus dengue 2 / Assessment of the cellular immune response induced in Balb/C mice with dengue virus 2 envelope protein
Vázquez, Beatriz Sierra
;
Díaz, Ana B. Pérez
;
Villasuso, Valexis Vásquez
;
Díaz, Rayner Rodríguez
;
Menéndez, Gissell García
;
Tirado, María Guadalupe Guzmán
.
Rev. cuba. med. trop
; 51(2): 95-98, May-Aug. 1999.
Artículo en Español | LILACS | ID: lil-333529
The
cellular immune response
to
dengue
type 2
virus envelope protein
was studied. To this end, the lympho-proliferative capacity of
T-lymphocytes
obtained from splenocytes of
animals
immunized with the
protein
when they were stimulated by such
protein
and
dengue
2
virus
. It was realized that splenocytes proliferated significantly in response to both types of
viral antigens
and that the values of stimulation indexes were higher in response to the whole
virus
than to the
protein
alone. Based on the above-mentioned, it was concludes that purified
dengue
2
virus envelope protein
was capable of generating specific and
memory
responses of
antigen
T-cell
to
dengue
2 type
virus
.
Asunto(s)
Animales
Masculino
Ratones
Virus del Dengue
Proteínas del Envoltorio Viral/inmunología
Ratones Endogámicos BALB C/inmunología
Inmunidad Celular
Biblioteca responsable:
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