Correlação entre medidas de proteína C-reativa pelos métodos de nefelometria e turbidimetria em pacientes com angina instável ou infarto agudo do miocárdio sem supradesnível do segmento ST / Correlation between turbidimetric and nephelometric methods of measuring C-reactive protein in patients with unstable angina or non-ST elevation acute myocardial infarction
Correia, Luis C. L; Lima, José C; Gerstenblith, Gary; Magalhães, Luis P; Moreira, Agnaluce; Barbosa Júnior, Octávio; Dumet, Juliana; Passos, Luiz Carlos S; D'Oliveira Júnior, Argemiro; Esteves, José Péricles.
Arq. bras. cardiol
; 81(2): 129-136, ago. 2003. tab, graf
Artículo
en Portugués, Inglés
| LILACS | ID: lil-345316
OBJECTIVE:
To evaluate the performance of the turbidimetric method of C-reactive protein (CRP) as a measure of low-grade inflammation in patients admitted with non-ST elevation acute coronary syndromes (ACS).METHODS:
Serum samples obtained at hospital arrival from 68 patients (66±11 years, 40 men), admitted with unstable angina or non-ST elevation acute myocardial infarction were used to measure CRP by the methods of nephelometry and turbidimetry.RESULTS:
The medians of C-reactive protein by the turbidimetric and nephelometric methods were 0.5 mg/dL and 0.47 mg/dL, respectively. A strong linear association existed between the 2 methods, according to the regression coefficient (b=0.75; 95 percent C.I.=0.70-0.80) and correlation coefficient (r=0.96; P<0.001). The mean difference between the nephelometric and turbidimetric CRP was 0.02 ± 0.91 mg/dL, and 100 percent agreement between the methods in the detection of high CRP was observed.CONCLUSION:
In patients with non-ST elevation ACS, CRP values obtained by turbidimetry show a strong linear association with the method of nephelometry and perfect agreement in the detection of high CRP
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BR1.1
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