Severe digestive pathology associated with chronic Chagas' disease in Ecuador: report of two cases
Guevara, A. G; Eras, J. W; Recalde, M; Vinueza, L; Cooper, P. J; Ouaissi, A; Guderian, R. H.
Rev. Soc. Bras. Med. Trop
; 30(5): 389-392, set.-out. 1997. ilus
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| LILACS | ID: lil-464356
DNA extracted from peripheral blood of two Ecuadorian patients showing severe digestive pathology was amplified by the polymerase chain reaction using a Trypanosoma cruzi specific oligonucleotide primers derived from the primary sequence of a cDNA encoding for a 24 kDa excretory/secretory protein. The positive PCR results together with the clinical findings confirmed that both patients had a digestive pathology due to Chagas' disease. This pathology could be more frequent than previously described in the chagasic endemic regions of Andean countries.
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