Intestinal metaplasia in gallbladders: prevalence study / Metaplasia intestinal na vesícula biliar: estudo da prevalência
Fernandes, José Eduardo Vasconcelos; Franco, Maria Isete Fares; Suzuki, Reinaldo Kenji; Tavares, Nelson Mattos; Bromberg, Sansom Henrique.
São Paulo med. j
; 126(4): 220-222, July 2008. ilus, tab
Artículo
en Inglés
| LILACS | ID: lil-494263
CONTEXT AND
OBJECTIVE:
Gallbladder cancer is usually diagnosed at a late stage and generally results in death. Discovery of predisposing factors for this neoplasia could prevent this outcome. In this study, we assess the presence of one of these factors intestinal metaplasia in gallbladders with stones and inflammatory processes. DESIGN ANDSETTING:
Cross-sectional study in Hospital do Servidor Público Estadual de São Paulo.METHOD:
The first 80 gallbladders from patients who underwent elective cholecystectomy between April and August 2002, presenting stones and chronic inflammation, were studied. The patients were divided into groups according to their age CC1, from 15 to 40 years; CC2, from 41 to 60 years; and CC3, from 61 to 85 years.RESULTS:
Twenty-one patients (26 percent) were male, while 59 (74 percent) were female. In the group CC1, intestinal metaplasia was present in 85.71 percent of the 21 patients studied; in CC2, in 79.41 percent of 34 patients; and in CC3, in 56.00 percent of 25 patients. These differences presented statistical significance (p = 0.04542).CONCLUSION:
Intestinal metaplasia is extremely frequent in gallbladders with inflammation and lithiasis, especially in younger patients.
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BR1.1
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